10 Best Spot Treatments for Cystic Acne in 2022

With so many options, finding the best spot treatment for cystic acne can be overwhelming. There are so many things to consider such as ingredients, formula, brand name, price, and so much more. Needless to say, this can be pretty time-consuming.

To save you the hassle, we researched hundreds of products and sifted through thousands of customer reviews. Then we checked the ingredients, formula, efficacy, and price. Based on this, we bring you the best spot treatment for cystic acne. Let’s have a look.

Top 10 Best Spot Treatments for Cystic Acne

Bestseller No. 1
Cystic Acne Spot Treatment for Teens & Adult | Sulfur 3% & Tea Tree Oil Pimple, Milia & Blemish Remover for Face & Body | Severe Hormonal Acne Treatment for Men & Women | 240+ Uses, 2-Pack by TreeActiv
  • ✅Not Just One But Two: Our cystic acne spot treatment clay now offers a pack of 2 jars, so you can cover more stubborn acne wherever they are. A small amount is enough, so each jar of this hormonal acne treatment for face & body will last long.
  • ✅Your Instant Acne Remedy: Unlike other anti-acne products, our clearing pimple cream spot treatment with Bentonite Clay & Pure Tea Tree Oil for acne provides rapid & visible results by unclogging pores, removing dirt, & lessening the look of redness.
  • ✅Offers 120+ Treatments Per Jar: Little goes a long way with our fast-acting acne face cream that shrinks zits fast. With Peppermint Oil, Eucalyptus Oil, Lemon Oil, & Spearmint Oil, our bacne & acne spot treatment solution is gentle on all skin types.
  • ✅Quick-Absorbing Zit Prevention Clay: Our dark acne spot corrector with a natural formula gets absorbed into the skin fast. This nighttime solution for marks & blemishes works well with our Acne Treatment Face Cream Moisturizer
  • ✅Comes With Pimple Patches: Our Aloe Vera & Sulfur acne treatment for active breakouts comes with cleansing Hydrocolloid patches in 3 sizes. Each acne patch or sticker targets every zit, dot, bump, whitehead, and blackhead, ensuring you're acne-free.
Bestseller No. 2
Cystic Acne Spot Treatment | Pimple, Milia, & Blemish Remover for Face & Body with Sulfur 3% & Tea Tree Oil | Blackhead, Whitehead, Zit, & Hormonal Acne Cream for Teens & Adults | 120+ Uses by TreeActiv
  • Get The Acne-Free Skin You Need: Our cystic acne treatment with pure Tea Tree Oil for face now offers twice the amount for the same price, so you can combat more stubborn zits; add this acne minimizer to your regimen to achieve blemish-free skin fast
  • Your Instant Acne Remedy: Unlike other products, our adult and teen zit clay wastes no time; our Sulfur and Bentonite pimple spot treatment offers rapid results by unclogging pores and lessening the look of acne, leaving your skin clearer and fresher
  • No More Redness And Irritation: You don't need to suffer in pursuit of beauty, so use our pimple cream spot treatment to say bye to breakouts; with only plant-based ingredients, our zit cream eliminates acne-causing irritants without causing discomfort
  • Offers 120+ Treatments: A little goes a long way with our cleansing acne cream that shrinks zits in no time, you'll be surprised by the good results when you wake up; our proactive acne spot treatment for face and body is ideal for all skin types too
  • Directions For Use: Apply a tiny amount of our zit, whitehead, and blackhead clay; rinse after 15 minutes; for best results, leave it overnight and use it with our hydrating Acne Treatment Face Spray and gentle Acne Treatment Face Cream Moisturizer
Bestseller No. 3
Cystic, Hormonal, and Severe Acne Treatment Cream for Teens & Adults Acne Treatment with Special Anti Acne Ingredients designed in USA and formulated in Japan (100ml/3.38oz)
  • Advanced Cystic Acne Treatment: Our cystic acne treatment cream reduces cystic acne and pimples, specially developed for all types of acne skin, gentle, moisturizing, and repairing by reducing oil production, speeding up skin cell turnover, soothing and reducing inflammation, which helps to prevent scarring.
  • A Unique Balanced Formula: cystic acne treatment cream contains Antibacterial, Anti-Acne ingredients that were carefully selected by professionals! SUNHEAL acne cream also includes Moisturizing and Repairing ingredients to help smooth and soften skin!
  • High Quality and Really Work: Our Acne Cream was designed in the US and formulated in Japan according to the strict standards. This cystic acne treatment cream doesn't contain any GMOs, artificial colors,! Remove pimples from your skin with our fast-absorbing face moisturizer for acne prone skin.
  • Directions For Use: Take an appropriate amount of this Cystic Acne Treatment Cream and apply it evenly on the acne-producing area of ​​the face and body like Back,Hip,,Chest,Neck,Shoulders andUpper arms.Apply it 3-4 times a day, or apply it 4-6 times if it is a serious condition for 4 weeks at least.
  • Positive Experience Guaranteed: We stand for your satisfaction with our products. We hope that you enjoy our acne treatment cream.Forget about breakouts and cystic acne, start to treat your skin right with Acne Treatment!
Bestseller No. 4
Acne Spot Treatment, Cystic Acne Treatment Natural Solution with Tea Tree Oil and Plant Extract for Treat Cystic Acne, Advanced Acne Removal, Fast-Acting, Pimple Repair - 30g
  • NATURAL FORMULA - Formulated with tea tree oil, purslane, honeysuckle, ginseng root, schisandra, North American Hamamelis and other herbal essences. Treats acne naturally and gently.
  • FAST ACTING - The concentrated formula works fast to cure acne, penetrating into the pores to clear its root.
  • TACKLES STUBBORN ACNE - The spot treatment tackles cystic acne effectively with its powerful ingredients.
  • ACNE PREVENTION - It works on your skin from the inside, killing the bacteria, to prevent future acne breakout.
  • DERMATOLOGIST RECOMMENDED - Tested and approved by dermatologists, this cream is sure to give you maximum relief.
Bestseller No. 5
Diva Stuff Cystic Acne Spot Treatment, Roller Ball, overnight Results – For Mild to Severe Acne with Salicylic Acid, Hawaiian Sea Extract, Hyaluronic Acid, Lactic Acid & Turmeric – Made in the USA
  • OVERNIGHT ACTION: Our fast absorbing formula heals acne by soothing inflammation, neutralizing acne-causing germs and shrinking pores. Specially designed to treat blemishes and cystic acne, this acne gel can be applied to forming and existing blemishes so that you can stop acne in its tracks.
  • UNIQUE, POWERFUL FORMULA: Contains Turmeric Hydrosol, Hawaiian Sea Extract, Tea Tree Oil, Wintergreen, Salicylic Acid, and more. We’ve blended some of the finest acne-busting ingredients to give your skin a royal skincare treatment. Salicylic Acid is known to reduce acne by unclogging pores and dissolving dead skin cells, while Turmeric is known to reduce inflammation and pimple scars.
  • MOISTURIZE SKIN WHILE FIGHTING ACNE: Hyaluronic Acid has shown to effectively keep skin surrounding acne from drying out. It’s also not known to clog pores because of its oil-free nature. We’ve blended Hyaluronic Acid into our acne spot treatment to exfoliate skin while delivering moisture and without causing dryness.
  • TEA TREE OIL, THE ACNE KILLER: Tea Tree Oil is well-known in the acne industry. It is traditionally used as a topical blemish shrinking and reducing agent.
  • THE DIVA STUFF GUARANTEE: At Diva Stuff, we live to create the best, most fun, and fairly priced beauty products possible. We are so confident that you'll love your Diva Stuff product that we stand by it 100%. We offer a lifetime satisfaction guarantee with each and every product we make.
SaleBestseller No. 6
DERMAKR Discreet Acne Pimple Patch | Spot Cover & Treatment Solution Cystic Acne & Pimple | Hydrocolloid Facial Stickers | Waterproof Patches Invisibly Cover Pimples
  • HEALS PIMPLES QUICKLY - This anti-acne patch will fix pimples quickly by drying them out and absorbing all the pus, irritants, dirt and other liquid discharge within and through the different layers of your skin, leaving an optimum healing environment for the skin to repair itself.
  • PREVENTS SCARS - Stay scar free while removing your acne when you use our pimple patch. This hydrocolloid patch soothes the irritated skin while protecting it from further infection, damage, scarring and scabbing over. The spot is also covered, preventing you from scratching and picking at it.
  • INVISIBLE PIMPLES IN AN INSTANT - Each discreet patch is made out of super, ultra-thin Hydrocolloid sheets, a biodegradable and transparent wound dressing. It covers the pimple, masking unwelcome outbreaks as the hydrocolloid sheets does its magic and continues to keep healing your skin.
  • DISCREET & LEAVES NO TRACE - Enjoy the absolute ZERO attention you and your pimples will receive - even from those you spend the whole day with - when you wear one of these acne dots. It is so thin and light that you'll forget it exists right there on your face, working hard to heal your skin.
  • AN ACTUAL CURE - This pimple patch is not just a "pimple symptom" treatment - but is also known to be an actual cure for acne in general. The Hydrocolloid material reduces oiliness, redness, and pigment changes while the physical patch keeps your hands off the pimple cosrx -which all help to resolve acne.
Bestseller No. 7
DRMTLGY Acne Spot Treatment and Cystic Acne Treatment. Acne Serum with Micronized Benzoyl Peroxide 5% and Glycolic Acid
  • QUICKLY FIGHTS ACNE BACTERIA ON THE SPOT. Treats acne breakouts, reduces pimples, whiteheads, and blackheads within 24 hours. Dissolves pore-clogging oils without over-drying your skin to effectively reduce future breakouts.
  • CONTAINS THE PUREST FORM OF BENZOYL PEROXIDE 5%. United States Pharmacopeia (USP) grade Benzoyl Peroxide 5% penetrates deep within the pores, eliminating current breakouts and preventing new ones. Proven as one of the most effective acne-fighting ingredients.
  • GLYCOLIC ACID 5% REDUCES ACNE SCARRING. Glycolic Acid in the form of sugar cane gently exfoliates to increase cellular turnover and remove cellular debris. This allows for a clearer complexion with a reduction in scarring.
  • REDUCES THE OIL IN PORES UP TO 85%. This acne serum is effective on the face, chest, and back to unclog pores, reduces redness, and inflammation.
  • DERMATOLOGIST RECOMMENDED ACNE TREATMENT SERUM. Our acne serum is safe for these skin types: dry, oily, combination, and normal. This formula is also paraben free, sulfate free, and cruelty free.
Bestseller No. 8
Ayadara Day And Night Cystic, Hormonal & Severe Acne Spot Treatment Kit, Salicylic Acid Daytime Cystic Acne Spot Treatment & Sulfur Overnight Acne Treatment
  • Bigger and Better: Our severe acne treatment jar now comes in a pack of two; Enjoy 120 uses of this pimple remover that offers rapid results whenever needed; Ayadara Warrior One and Two doubles as an acne spots treatment for the face
  • All Types of Acne: Eliminate all forms of acne with our natural acne treatment with Tea Tree oil; This acne treatment also functions as arm, leg, neck, chest, shoulder, butt, thigh, and back acne treatment without causing skin irritation
  • Shrinks Impurities Overnight: With quick acne fighting ingredients such as sulfur, witch hazel, lemon oil, bentonite clay, it can penetrate fast and efficiently; This hormonal acne treatment works as zit, blemish, and acne dark spot remover
  • Versatile Cystic Acne Treatment: Minimize redness and swelling of pimples with our acne treatment for sensitive skin; It acts as a blackhead, whitehead and acne remover, suitable body acne treatment for teens, adult acne treatment for women and men
  • High Quality: Our cystic acne spot treatment has no parabens, sulfates, palm oil, and other harmful chemicals; Use this potent overnight acne treatment with our Warrior One and Breakout Warrior with Salicylic Acid for best results
Bestseller No. 9
Cystic Hormonal & Severe Acne Spot Treatment for Face | Overnight Cystic Acne Treatment for Teens, Women, & Men with Sensitive Skin | Blind Pimple & Blemish Remover Cream | 120+ Treatments by Ayadara
  • A Little Goes a Long Way: Our Warrior Two Cystic Acne Treatment provides over 120 uses in an easy to carry travel sized container; Fight stubborn cystic, hormonal and severe acne overnight and clear out large areas of acne in 4 weeks with this fast acting formula
  • Harnessing the Power Of Nature: Our Overnight Spot Treatment is packed with the goodness of Bentonite Clay, Aloe Vera, Witch Hazel, Tea Tree, Peppermint, Lemon Oil, Spearmint, Eucalyptus, and Pink Grapefruit; Our freshly scented plant based formula uses natural ingredients instead of chemicals
  • Safe for Sensitive Skin: Achieve clear and moisturized skin without dryness and irritation; Gently massage a tiny amount onto affected areas, wait for 30 minutes before rinsing or leave it on all night; For best results, use with Ayadara Breakout Warrior and Warrior One Spot Treatment
  • Experience Ayadara's Third Eye Chakra Collection: The Chakra of wisdom and vision is located on the forehead between the eyebrows; Keep your Third Eye balanced for clarity; Emanate radiance and bring back the true vision of what’s beautiful: You
  • Better for You, Better for Mother Earth: No toxins, harsh chemicals, parabens, sulfates, phthalates, palm oil, or controversial synthetics; We are dedicated advocates of natural ingredients because we care not only for our customers, but everything else on the planet: animals, plants, and nature itself
Bestseller No. 10
Acne Spot Treatment Balm - Made in USA - Effective Acne Scar Treatment for Face and Body Acne - Cystic Acne Treatment with Tea Tree Oil - Natural and Gentle - Acne Treatment for Teens and Adults, 2 oz
  • More than an Acne Cream - If you are looking for a natural and fast-acting acne scar remover to combat pimples, acne spots, and breakouts - you just found it! Being extremely effective and Natural our acne cream is capable of dealing with even the most complicated cases like cystic acne and post-acne scars.
  • Powerful Acne Remover - Our potent herbal formula brings excellent results due to the supreme science-backed ingredients, well known for their acne treatment and breakout preventing properties. Tea Tree Oil, Arnica Montana, Aloe Vera, Rosemary Oil, Coconut Oil and Jojoba Oil are only some of them.
  • Unique American Formula - With these natural ingredients, our herbal balm do not only solve the pimple problem but prevent it even before it starts. The special formula helps follicles to not get blocked, and oil does not build up under the skin, so you can tackle the reason and not the symptom. Stop new acne from forming and greatly benefit skin's texture and tone.
  • Safe for Any Age and Skin Type - Creating our product with care for your health, we use only top-quality ingredients and manufacture only in the USA according to the strictest US standards. Natural, Non-GMO, no artificial color or fragrance, alcohol free! Be sure that you are buying the highest quality product!
  • Clear Skin Guarantee - Here, at GRAMRIGHT we're working day and night to create the best solving-all-your-problems formula, and we're sure that we have already reached respectable results. But if for some reason, your customer experience was not excellent - contact us immediately, and we'll make the things right.

Things to Consider When Buying the Best Spot Treatments for Cystic Acne

Ingredients

When it comes to choosing the best spot treatment for cystic acne, the most important thing to consider is the ingredients. If you’re particularly allergic to a specific ingredient, make sure to only choose products that don’t contain it. This way, you won’t experience allergies or irritation when using a spot treatment.

Price

Another important thing to consider is the price. You shouldn’t always chase the cheapest product on the market as it can cause problems in the long run. Similarly, just because a product is expensive doesn’t mean that it’s the right product for you. Make sure to do your due diligence when shopping for the best spot treatment for cystic acne.

Avoid Harsh Chemicals

When looking for the best spot treatment for cystic acne, it’s better to avoid harsh chemicals. Generally, it’s better to look for a product that doesn’t contain synthetic fragrances, parabens, sulfates, phthalates, etc. Even the reputable products can sometimes contain these chemicals, it’s important to look at the formula. Too much of these chemicals can be bad for you.

Star Rating

If a product is well-received on Amazon, chances are it’s usually pretty good. These reviews are generally a testament to the efficacy of a product. When shopping for the best spot treatment for cystic acne, you should usually go with product with the star rating of 3. 5 or more. The higher the better!

Read Customer Reviews

Reading customer reviews can also be helpful when purchasing the best spot treatment for cystic acne. It’s possible that someone else who has the same needs as you has already tried and reviewed the product. Reading their review will give you an idea on whether or not the spot treatment you’re looking to buy is worth your time and money.

Brand Name

Finally, when it comes to beauty, skincare, or hair care products, it’s usually better to stick with reputable products. There are so many products available on the market, but the brands which have stood the test of time are the ones that you should generally go for. At the same time, don’t be afraid of experimenting with new products.

Patch Test

No matter which spot treatment you’re considering, it’s important to do a patch test first (even if a product is well-received). Everyone is different and so are their needs. So, always be sure to do a patch test when you try out a new product.

Conclusion

It can be challenging to find the best spot treatment for cystic acne. However, we’ve done all the heavy-lifting for you. We hope this article helped you find the best spot treatment for your needs.

Which one of these spot treatments are you going to try? Let us know in the comments below. If you have any questions, ask away.

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