10 Best Night Creams for Acne-Prone Skin in 2022

With so many options, finding the best night cream for acne-prone skin can be overwhelming. There are so many things to consider such as ingredients, formula, brand name, price, and so much more. Needless to say, this can be pretty time-consuming.

To save you the hassle, we researched hundreds of products and sifted through thousands of customer reviews. Then we checked the ingredients, formula, efficacy, and price. Based on this, we bring you the best night cream for acne-prone skin. Let’s have a look.

Top 10 Best Night Creams for Acne-Prone Skin

SaleBestseller No. 1
Night Cream with Hyaluronic Acid by the Makers of Differin Gel, Restorative Night Moisturizer, Gentle Skin Care for Acne Prone Sensitive Skin, 2.5 Oz (Packaging May Vary)
  • Hydrating formula with hyaluronic acid, ceramides, and allantoin to visibly improve skin texture by hydrating dry skin overnight
  • Hyaluronic acid is naturally found in skin and binds to water to help retain natural moisture and keep skin looking plump
  • Ceramides help maintain and restore the skin barrier to lock in moisture for a full 24 hours
  • Allantoin soothes dry, flaky skin
  • Dermatologist developed and tested formula that is non irritating, fragrance free, and non comedogenic
Bestseller No. 2
[CRAZY SKIN] Skin Repair Trouble Care Sleeping Cream 1.76oz | Deep Moisturizing pH level 5.5 overnight cream | Moisturizer for acne prone skin | Korean skin care | night cream sleeping mask recovery care
  • 🌙 Lupeol(eggplant extract) : moisturizes & supports skin without worrying about irritating your delicate condition.
  • 🌙 Salicylic acid: helps to unclog pores and gently exfoliates skin, which is best for acne prone skin
  • 🌙 Hydrate, Brighten & Smooth: Seven plants, herbal extracts, and aloe help to quench thirsty skin and renew your skin, by strengthening the skin barrier
  • 🌙 Calms down & Rejuvenate your sensitive skin: Mild ph acid 5.5(5.3~5.9) overnight cream is suitable for breakout-prone skin.
  • 🌙 Essence formula: absorbs instantly without feeling greasy 🎁 Perfect Gift Options are available for your convenience!
Bestseller No. 3
Plum Skin Renewing Night Face Gel with Green Tea & Glycolic Acid for Oily & Acne Prone Skin, Hydrating Moisturizer for Dry Skin, Gentle for Sensitive Skin, Paraben & Cruelty Free for Women,1.69 Fl OZ
  • The ultra-light Plum Green Tea Night Gel with glycolic acid ensures no more oily mornings. It is a night gel with an ultra-light gel texture that is pillow-proof and leaves your skin non-greasy and fresh the next morning. It is best suited for oily and acne-prone skin.
  • This night gel contains non-comedogenic ingredients. Glycolic acid sweeps away skin debris and prepares the skin for self-renewal. It works wonders with all your pigmentation issues. Our goodness chemists know exactly what's required to do the job without overdoing it.
  • Argan oil provides balanced hydration and helps skin retain moisture overnight, leaving your skin fresh and nourished. Rich in essential fatty acids, or EFAs, which support the health and beauty of the skin and hair it is the perfect ingredient for regulating sebum production to keep the skin’s natural oils at a healthy level. It can help to treat several different types of acne and promotes a smoother, calmer complexion.
  • Antioxidant Green tea extracts help combat acne and have a concentrated source of polyphenols and other antioxidants, to stop the acne formation cycle in its tracks. Oxidation of skin-produced sebum is a key step in acne formation – something we are looking to stop here. In doing so it leaves behind brighter and glowing skin!
  • Plum Renewed Clarity Night Gel, Green Tea is 100% vegan. This moisturizing night gel is paraben-free, phthalate-free, and cruelty-free as always. It works on oily, acne-prone, and combination skin for overnight repairs.
Bestseller No. 4
Neutralyze Renewal Complex Moisturizer for Acne Prone Skin - Time Released, Medical Grade 2% Mandelic Acid & Salicylic Acid Moisturizer Cream - Acne Moisturizer Cream for Face & Acne Lotion (90+ Day)
  • TIME RELEASED A.H.A. + B.H.A. MOISTURIZER FOR ACNE PRONE SKIN: Multi-tasking face moisturizer cream for acne prone skin & acne cream (large 3.4 oz/90+ day supply). Perfect for dry, oily and combination skin. This maximum strength acne moisturizer contains time-released, medical grade 2% salicylic acid & mandelic acid to remove acne, increase cellular turnover and gently exfoliate.
  • SCIENCE INSPIRED FORMULATION WITH PATENTED, ADVANCED OIL CONTROL TECHNOLOGY: Contains patented, advanced oil control technology to quickly absorb into skin and deeply penetrate, removing excess oil trapped in pores. Improves skin elasticity for fewer fine lines & wrinkles.
  • FAST ABSORBING, HYDRATING FACE CREAM FOR ACNE PRONE SKIN: This multi-purpose, hydrating facial moisturizer cream goes on clean and instantly hydrates skin. Beautifully lightweight and formulated to absorb quickly so you can layer SPF and/or makeup as needed. Suitable for all skin types, safe for sensitive skin. Perfect for women and men, adults and teens.
  • FIGHTS ACNE, HYDRATES & PREVENT FUTURE BREAKOUTS: This multi-functional, oil free acne moisturizer cream provides an all-in-one solution for several concerns. Save time and money by using this combination day moisturizer & acne lotion with anti aging skincare benefits.
  • SEE AMAZING RESULTS OR YOUR MONEY BACK: If unsatisfied, email us directly for a 100% refund (keep the product!). Neutralyze is a dermatologist-recommended medication for the treatment of acne vulgaris. USA-made in a certified cGMP/SOP compliant facility, 100% cruelty-free (never tested on animals). No parabens or sulfates.
SaleBestseller No. 5
Era Organics Tea Tree Oil Face Cream - For Oily, Acne Prone Skin, Extra Soothing & Nourishing Non-Greasy Botanical Facial Moisturizer with 7X Ingredients For Rosacea, Cystic Acne, Blackheads & Redness
  • NUTRIENT-RICH TEA TREE FACE CREAM FOR OILY SKIN. Using Tea Tree Oil for acne is a centuries old natural remedy that still works today. Our face moisturizer for oily skin is perfect for helping with blemishes, blackheads, cystic acne, redness and combination skin. Get balanced, smoother and clearer looking skin.
  • BALANCING & CALMING EXTRA STRENGTH MOISTURIZER CREAM. Most acne treatments are too harsh on the skin, leading to irritation, redness or dry skin that needs support. Our facial cream is formulated to soothe, provide nourishment and balance oily skin, dry skin or combination skin to support your treatments in fighting blemishes. Gentle facial moisturizer perfect for men, women and teens.
  • TEA TREE & SALICYLIC ACID CREAM WITH INGREDIENTS YOUR SKIN WILL LOVE. We combine powerful botanical, food grade ingredients to nourish and balance the skin, including: St. John’s Wort, Pomegranate Seed Oil, Salicylic Acid, Zinc, Burdock Root, Dandelion Root and Goldenseal.
  • AS SAFE AS IT IS EFFECTIVE. Our premium, plant based face cream is gentle on pores and vegan friendly. To make sure people with sensitive skin can use it, it also has no parabens, no hormone disruptors, no harsh chemicals and gentle, yet effective at helping moisturize all skin types.
  • TRY IT NOW WITH CONFIDENCE. Era Organics is family owned and operated so customer service and pleasure are our top priority. Blemishes, redness and oily skin can happen to anyone, no matter what you use. So if you’re not completely satisfied, just let us know and we’re happy to help.
SaleBestseller No. 6
Neutralyze Intensive Night Cream for Face - Medical Grade Bakuchiol, Vitamin C & 2% Salicylic Acid Moisturizer Lotion - Maximum Strength Anti Aging & Anti Acne Moisturizer Cream for Women (90+ Day)
  • DERMATOLOGIST FORMULATED REJUVENATING NIGHT CREAM: An advanced, nourishing night moisturizer for face & body is absolutely essential to complete your every day skincare routine. Neutralyze Intensive Night Cream is a medical-grade Vitamin C, Bakuchiol (retinol alternative) & 2% Salicylic Acid lotion, a rejuvenating over night cream for women & men with aging, acne prone skin. Suitable for all skin types and skin tones! (Large 3.4 oz/90+ day supply)
  • MULTIPURPOSE ANTI ACNE & ANTI AGING FACE MOISTURIZER FOR WOMEN & MEN: Finally, an all-in-one nightly face cream for acne prone skin & anti aging! This award-winning formula promoted cell turnover and gently exfoliates, while hydrating to soothe redness caused by acne, restoring skin’s natural balance. Acne prone and aging skin needs powerful nightly intervention to combat irritation and other inflammation markers commonly associated with acne.
  • BAKUCHIOL SERUM (RETINOL ALTERNATIVE) IN AN ADVANCED NIGHT CREAM: Discover the effectiveness of bakuchiol, a plant-based natural alternative to retinol. Clinical studies have shown that bakuchiol prevents fine lines & wrinkles, and helps with pigmentation, elasticity, and firmness.
  • TAKE BEAUTY SLEEP TO A WHOLE NEW LEVEL: Formulated to reinvigorate your skin & nighttime skincare routine to improve skin texture, reduce the appearance of fine lines & wrinkles, and combat overdrying while you sleep. Experience the highest quality skin care ingredients using this night moisturizer for face & body that goes to work while you rest!
  • SEE AMAZING RESULTS OR YOUR MONEY BACK: If unsatisfied, email us directly for a 100% refund (keep the product!). Neutralyze is a dermatologist-recommended medication for the treatment of acne vulgaris. USA-made in a certified cGMP/SOP compliant facility, 100% cruelty-free (never tested on animals). No parabens or sulfates.
SaleBestseller No. 7
Sheamoisture Face Moisturizer for Acne-Prone Skin African Black Soap with Shea Butter 2 oz
  • In this Shea Moisture Hydrating Gelee face moisturizer, African Black Soap and Bamboo Charcoal clarifies and infuses lightweight moisture; use as and anti aging moisturizer and moisturizing cream.
  • Made with Shea Butter and a moisture-rich blend, this face moisturizer creates an acne face moisturizer, gel skin cream and facial lotion that gives oily, blemish-prone skin clarifying balance.
  • Also made with Cooling Aloe, this face lotion and moisturizer for oily skin, moisturizing cream or gel face serum soothes and nourishes, leaving skin feeling hydrated, smooth and refreshed.
  • After cleansing and toning, apply this hydrating face cream, night face cream and sensitive skin moisturizer onto face and neck with upward motions; make it your daily face moisturizer.
  • This gel face cream has no Parabens, Phthalates, Mineral Oil, Sulfates, plus our face lotion and anti-aging cream moisturizer has no Animal Testing.
Bestseller No. 8
Dr. Different VITAACNAL TX Night Cream for Face - Soothing & Nourishing Retinal Sebum Control Night Cream For Acne-Prone Skin - Blackheads Care Oil-Free Treatment Removes Dead Skin Cells 0.7oz.
  • [DESIGNED TO BE 100% EFFICIENT] Vitaacnal TX Night Cream from Dr. Different is a perfect anti-aging night cream as it increases skin renewal & revitalization while you sleep. This face cream shows maximum effects due to the liposome technology and you can achieve effective results in a very short time.
  • [RETINAL, WHY IT’S BETTER THAN RETINOL] Clinical studies show retinal works up to 11 times faster than retinol, in addition to having a much higher exfoliation rate than retinol. Retinal is the best remedy since it gives better and faster results without causing any adverse reactions.
  • [SAFE TO USE] The face skin care cream is clinically tested and recommended by dermatologists. It’s completely safe to use and does not cause any side effects like rash, irritation, redness. Hyaluronic acid in this anti-aging treatment cream is another component that significantly reduces deep wrinkles and enhances skin firmness.
  • [BEST FOR TREATING OIL PROBLEMS AND ACNE] Acne control night cream is especially effective in reducing and treating acne symptoms. The skin care cream is designed to be used on oily skin and to control sebum production by interacting with the sebaceous glands. This acne treatment contains retinal, the main ingredient recommended by dermatologists for the treatment of acne
  • [BEST FOR SKIN MOISTURIZATION] This retinal cream for face shows its effects by boosting the water portion in the Stratum Corneum (skin’s external surface). This feature provides effective treatment against skin dryness and roughness problems. Doesn’t occlude or seal the pores and cuts down transepidermal water loss. Which again is a contributor towards moisturization
Bestseller No. 9
AYADARA Moisturizing Acne Treatment Cream, Salicylic Acid Face Moisturizer for Oily & Acne Prone Skin, Pimple, Blackhead, Whitehead, Hormonal, & Cystic Acne Treatment for Men, Women, 90-Day Supply
  • Eliminates Stubborn Acne: Get clear skin fast with our acne face moisturizer that helps in diminishing the look of pimples. We achieve this with our potent natural ingredients like Jojoba Oil, Witch Hazel, Green Tea Extract, and Tea Tree oil.
  • Acne Treatment And Prevention: Our acne face cream contains natural cruelty-free ingredients that help unblock sebaceous glands, tighten pores while locking in needed moisture. This helps in balancing oil production for eliminating skin impurities.
  • Moisturizes And Soothes: As it cleanses clogged pores from excess oil, this acne spot treatment can also be used as a salicylic acid lotion for face moisturizer for acne prone skin and face cream for dark spots while hydrating your skin.
  • Gentle Acne Cream For Face: This pimple cream is formulated as an acne treatment and suitable for clearing dirt within the pores for sensitive skin that triggers breakouts. With continued use, this acne moisturizer will leave your skin feeling smooth.
  • No Burning Sensation: Ayadara's Salicylic Acid acne treatment uses earth-grown, skin-friendly ingredients that work together to combat acne dots and dark spots. Apply this zit cream after using our Cystic, Hormonal & Severe Acne Charcoal Face Wash.
SaleBestseller No. 10
Simplified Skin 2.5% Retinol Cream Face Moisturizer w/ Vitamin E & Hyaluronic Acid for Wrinkles & Acne - Eye Cream - Anti Aging Facial Skin Care Products - Night & Day Moisturizer Face Cream 1.7 oz
  • Active Retinol: Our 2.5% active Retinol cream is the strongest non-prescription Retinol on the market. It helps increase cell turnover & stimulates collagen production to give your skin a youthful appearance that will make you feel younger than ever.
  • Anti-Aging Cream: Fight signs of aging with this face cream for women. Our non-greasy face lotion reduces dark spots, hyperpigmentation, wrinkles, fine lines, and sun damage for flawless skin.
  • Face Moisturizer: It's made w/ Vitamin E, Vitamin B5, Hyaluronic Acid, Shea Butter, Green Tea & Jojoba oil to naturally moisturize & regenerate your skin. Our natural blend of ingredients work to reduce acne, scars, and dark circles for healthy skin.
  • Safe For All Skin Types: This cream is non-toxic and free from harmful chemical substances like fragrances, dyes, and parabens, and it works on all skin types. Use this Day & Night cream for brighter-looking skin that you'll have to see to believe.
  • Made in the USA: Our anti-wrinkle retinol cream for the face is cruelty-free, Paraben-free, Sulfate-free, Gluten-free, and Fragrance-free. It's also formulated and bottled in the USA. Try our Retinol moisturizer today for smoother and younger-looking skin.

Things to Consider When Buying the Best Night Creams for Acne-Prone Skin


When it comes to choosing the best night cream for acne-prone skin, the most important thing to consider is the ingredients. If you’re particularly allergic to a specific ingredient, make sure to only choose products that don’t contain it. This way, you won’t experience allergies or irritation when using a night cream.


Another important thing to consider is the price. You shouldn’t always chase the cheapest product on the market as it can cause problems in the long run. Similarly, just because a product is expensive doesn’t mean that it’s the right product for you. Make sure to do your due diligence when shopping for the best night cream for acne-prone skin.

Avoid Harsh Chemicals

When looking for the best night cream for acne-prone skin, it’s better to avoid harsh chemicals. Generally, it’s better to look for a product that doesn’t contain synthetic fragrances, parabens, sulfates, phthalates, etc. Even the reputable products can sometimes contain these chemicals, it’s important to look at the formula. Too much of these chemicals can be bad for you.

Star Rating

If a product is well-received on Amazon, chances are it’s usually pretty good. These reviews are generally a testament to the efficacy of a product. When shopping for the best night cream for acne-prone skin, you should usually go with product with the star rating of 3. 5 or more. The higher the better!

Brand Name

Finally, when it comes to beauty, skincare, or hair care products, it’s usually better to stick with reputable products. There are so many products available on the market, but the brands which have stood the test of time are the ones that you should generally go for. At the same time, don’t be afraid of experimenting with new products.

Patch Test

No matter which night cream you’re considering, it’s important to do a patch test first (even if a product is well-received). Everyone is different and so are their needs. So, always be sure to do a patch test when you try out a new product.


It can be challenging to find the best night cream for acne-prone skin. However, we’ve done all the heavy-lifting for you. We hope this article helped you find the best night cream for your needs.

Which one of these night creams are you going to try? Let us know in the comments below. If you have any questions, ask away.

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