10 Best Eye Drops for Dry Eyes in 2022

With so many options, finding the best eye drops for dry eyes can be overwhelming. There are so many things to consider such as ingredients, formula, brand name, price, and so much more. Needless to say, this can be pretty time-consuming.

To save you the hassle, we researched hundreds of products and sifted through thousands of customer reviews. Then we checked the ingredients, formula, efficacy, and price. Based on this, we bring you the best eye drops for dry eyes. Let’s have a look.

Top 10 Best Eye Drops for Dry Eyes

SaleBestseller No. 1
Refresh Tears Lubricant Eye Drops, 2 Count (Pack of 1)
  • Original strength formula
  • Relieves mild symptoms of eye dryness
  • Instantly moisturizes and lubricates
  • Designed to act like your own natural tears
  • Doctor recommended with over 30 years of experience; REFRESH Family of Products, Ipsos Healthcare, 2021 REFRESH ECP Recommendation Survey.
SaleBestseller No. 2
Systane Ultra Lubricant Eye Drops, Twin Pack, 10-mL Each,packaging may vary
  • #1 Dr Recommended Brand of Artificial Tears*, packaging may vary
  • Extended Protection
  • Fast Long-Lasting Dry Eye Symptom Relief.Store at room temperature
  • Reduces both the signs and symptoms of dry eye
  • Quickly soothe irritated eyes wherever you are
Bestseller No. 3
Biotrue® Hydration Boost Eye Drops, Soft Contact Lens Friendly for Irritated and Dry Eyes from Bausch + Lomb, Preservative Free, Naturally Inspired, 0.33 FL OZ (10 mL), Pack of 2
  • NATURALLY INSPIRED INGREDIENTS: Biotrue Hydration Boost Eye Drops are enhanced with HA (Hyaluronan), Antioxidant, and Electrolyte and provide instant moisture for dry eyes.
  • CONTACT LENS FRIENDLY: Biotrue Hydration Boost Eye Drops can be applied while wearing soft contact lenses.
  • INSTANT MOISTURE: For dry, irritated eyes due to screen and environmental stressors.
  • BIOTRUE EYE DROPS: Not only are the Hydration Boost Eye Drops free of preservatives but they are also pH balanced.
  • EYE DROPS & MORE: Bausch + Lomb makes eye care products you can trust, from contact lens solution to eye drops, vitamins, & ointments to help your eyes feel moisturized and protected.
SaleBestseller No. 4
Systane COMPLETE PF Multi-Dose Preservative Free Dry Eye Drops 20ml(Pack of 2 – 10mL bottles)
  • Fast acting hydration for sensitive eyes
  • Preservative free tear evaporation protection
  • Nano droplets for better coverage
Bestseller No. 5
Systane Ultra Lubricant Eye Drops,0.14 Fl Oz (Pack of 1)
  • #1 Dr Recommended Brand of Artificial Tears*
  • Extended Protection
  • Fast Long-Lasting Dry Eye Symptom Relief
  • Reduces both the signs and symptoms of dry eye
  • Quickly soothe irritated eyes wherever you are
SaleBestseller No. 6
Clear Eyes Triple Relief Eye Drops, Relieves Redness & Calms Irritation, 0.5 Fl Oz
  • Clear Eyes Triple Relief Eye Drops provide complete relief for dry, red and irritated eyes
  • Enhanced moisturization contains lubricants to soothe and moisturize eyes versus Clear Eyes Redness Relief and Clear Eyes Maximum Redness Relief
  • Calms irritated eyes, relieves redness and helps to protect against further irritation
  • Relieves redness and irritation due to dryness of the eye
  • Provides up to 12 hours of soothing comfort
  • Contains 1 bottle of Clear Eyes Triple Relief Eye Drops, 0.5 fl oz
  • FSA- and HSA-eligible product in the U.S.
Bestseller No. 7
Refresh Plus Lubricant Eye Drops, Preservative-Free, 0.01 Fl Oz Single-Use Containers, 50 Count, Packaging May Vary
  • Original strength, preservative-free formula
  • Relieves mild symptoms of eye dryness
  • Instantly moisturizes and lubricates
  • Designed to act like your own natural tears
  • Great for sensitive eyes
  • Value size: 50 on-the go, single-use vials
  • Can be used after LASIK or other eye surgeries. Follow your eye doctor's instructions if you are using REFRESH RELIEVA PF after an eye surgery (e.g., LASIK) to relieve dryness and discomfort.
  • The brand in preservative-free artificial tears; REFRESH Family of Products, Ipsos Healthcare, 2021 REFRESH ECP Recommendation Survey.
SaleBestseller No. 8
Ocusoft Retaine MGD Ophthalmic Emulsion, Milky White Solution, 30 count Single Use Containers, 0.01 Fluid Ounce
  • Retained mgd is a revolutionary preservative-free ophthalmic emulsion that moisturizes, lubricates and protects moderate to severe dry eyes
  • Provides long-lasting relief utilizing nova orb,
  • Proprietary cationic oil emulsion technology that effectively delivers ingredients through electrostatic attraction between positively charged droplets and the negatively charged ocular surface
  • Retained MGD is a revolutionary preservative-free ophthalmic emulsion that moisturizes, lubricates and protects moderate to severe dry eyes.
  • Provides long-lasting relief utilizing Nova orb,
  • proprietary cationic oil emulsion technology that effectively delivers ingredients through electrostatic attraction between positively charged droplets and the negatively charged ocular surface.
  • The hypo tonicity of the emulsion adds moisture by lowering the salt concentration of tears while the lipid component lubricates and protects the surface of the eye.
  • Retained MGD is a revolutionary preservative-free ophthalmic emulsion that moisturizes, lubricates and protects moderate to severe dry eyes.
  • Provides long-lasting relief utilizing Nova orb,
  • proprietary cationic oil emulsion technology that effectively delivers ingredients through electrostatic attraction between positively charged droplets and the negatively charged ocular surface.
Bestseller No. 9
2 PK Artificial Tears Eye Drops for Dry Eyes - Extra Strong Moisturizing Lubricating Eye Drops - Potent Concentration for Fast Acting Dry Eye Relief - 30mL by EzriCare
  • TWIN PACK ARTIFICIAL TEARS - These artificial tears eye drops from EzriCare come in a twin pack with two 15mL (0.5 oz) bottles. Our hypotonic and balanced electrolyte formula is preservative free & replicates healthy tears to naturally lubricate eyes when dry, red, scratchy, itchy, or gritty.
  • HIGHER CONCENTRATION FORMULA (1%) - Our proprietary natural tears formula utilizes a 1% concentration of Carboxymethylcellulose Sodium vs. the industry standard 0.5-0.6% concentration. Compares to the active ingredients in REFRESH, but more potent.
  • FAST ACTING DRY EYE RELIEF - Choose EzriCare for instant long-lasting relief when you need it any time of the day or night. Our natural tears eye drops feel smooth, cool, and calming as they moisturize dry and irritated eyes without blurring your vision.
  • SOOTHING MOISTURIZING LUBRICANT - The dry eyes eye drops are smooth and liquid cooling as they enter the eye, without the gunky feeling of other brands that leave your eyelashes wet and stuck together or cause blurry vision. Double factory sealed for your protection.
  • SMALL CONVENIENT TRAVEL SIZE - Our moisturizing eyedrops come in a convenient twin pack with two small 15mL (0.5 oz) bottles. The smaller bottle size easily fits into your pocket, purse, or backpack for on-the-go travel-ready dry eye relief when you need it.
SaleBestseller No. 10
iVIZIA Sterile Lubricant Eye Drops for Dry Eyes, Preservative-Free, Moisturizing, Dry Eye Relief, Contact Lens Friendly, 0.33 fl oz bottle
  • Your Dry Eyes Deserve Better: iVIZIA Dry Eye drops are scientifically formulated to moisturize and lubricate dry eyes and relieve discomfort and eye strain due to dryness
  • Unique Formulation: Hydrating polymers form a protective matrix, moisturizing Hyaluronic Acid holds up to 1000x its weight in moisture, and Trehalose (synthetic ingredient also found in desert plants)
  • Free of Irritating Preservatives: Sterile, safe for use with contact lenses, and can be used before or after eye surgery
  • Patented ABAK Bottle: prevents microbial contamination while staying preservative-free, dispenses drop-by-drop, and does not stream. The ergonomic bottle is easy to open, easy to hold and squeeze
  • iVIZIA – We See a Better Way: for healthy, comfortable eyes from the makers of the #1 doctor-prescribed dry eye brand in Europe.

Things to Consider When Buying the Best Eye Drops for Dry Eyes

Ingredients

When it comes to choosing the best eye drops for dry eyes, the most important thing to consider is the ingredients. If you’re particularly allergic to a specific ingredient, make sure to only choose products that don’t contain it. This way, you won’t experience allergies or irritation when using a eye drops.

Price

Another important thing to consider is the price. You shouldn’t always chase the cheapest product on the market as it can cause problems in the long run. Similarly, just because a product is expensive doesn’t mean that it’s the right product for you. Make sure to do your due diligence when shopping for the best eye drops for dry eyes.

Avoid Harsh Chemicals

When looking for the best eye drops for dry eyes, it’s better to avoid harsh chemicals. Generally, it’s better to look for a product that doesn’t contain synthetic fragrances, parabens, sulfates, phthalates, etc. Even the reputable products can sometimes contain these chemicals, it’s important to look at the formula. Too much of these chemicals can be bad for you.

Star Rating

If a product is well-received on Amazon, chances are it’s usually pretty good. These reviews are generally a testament to the efficacy of a product. When shopping for the best eye drops for dry eyes, you should usually go with product with the star rating of 3. 5 or more. The higher the better!

Read Customer Reviews

Reading customer reviews can also be helpful when purchasing the best eye drops for dry eyes. It’s possible that someone else who has the same needs as you has already tried and reviewed the product. Reading their review will give you an idea on whether or not the eye drops you’re looking to buy is worth your time and money.

Brand Name

Finally, when it comes to beauty, skincare, or hair care products, it’s usually better to stick with reputable products. There are so many products available on the market, but the brands which have stood the test of time are the ones that you should generally go for. At the same time, don’t be afraid of experimenting with new products.

Patch Test

No matter which eye drops you’re considering, it’s important to do a patch test first (even if a product is well-received). Everyone is different and so are their needs. So, always be sure to do a patch test when you try out a new product.

Conclusion

It can be challenging to find the best eye drops for dry eyes. However, we’ve done all the heavy-lifting for you. We hope this article helped you find the best eye drops for your needs.

Which one of these eye dropss are you going to try? Let us know in the comments below. If you have any questions, ask away.

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