10 Best Drugstore Night Creams for Acne Prone Skin in 2022

With so many options, finding the best drugstore night cream for acne prone skin can be overwhelming. There are so many things to consider such as ingredients, formula, brand name, price, and so much more. Needless to say, this can be pretty time-consuming.

To save you the hassle, we researched hundreds of products and sifted through thousands of customer reviews. Then we checked the ingredients, formula, efficacy, and price. Based on this, we bring you the best drugstore night cream for acne prone skin. Let’s have a look.

Top 10 Best Drugstore Night Creams for Acne Prone Skin

SaleBestseller No. 1
CeraVe PM Facial Moisturizing Lotion | Night Cream with Hyaluronic Acid and Niacinamide | Ultra-Lightweight, Oil-Free Moisturizer for Face | 3 Ounce
  • [ OIL FREE NIGHT LOTION ] Use Cerave PM facial lotion as the last step in an evening skincare routine. If layering with an eye cream, moisturizer or facial serum, apply the Cerave night lotion after other product applications have been fully absorbed
  • [ OVERNIGHT MOISTURIZER ] Cerave’s PM face cream contains niacinamide to help calm the skin and uses MVE Technology to deliver hydration throughout the night. It also contains hyaluronic acid to help retain skin's moisture
  • [ ESSENTIAL CERAMIDES ] Ceramides are found naturally in the skin and make up 50% of the lipids in the skin barrier. All CeraVe products are formulated with three essential ceramides (1, 3, 6-II) to help restore and maintain the skin’s natural barrier
  • [ DERMATOLOGIST RECOMMENDED ] CeraVe Skincare is developed with dermatologists and has products suitable for dry skin, sensitive skin, oily skin, acne-prone, and more
  • [ GENTLE ON SKIN ] Fragrance free, paraben-free, oil free, non-comedogenic, and allergy-tested
SaleBestseller No. 2
CETAPHIL Daily Hydrating Lotion for Face ,With Hyaluronic Acid, 3 fl oz, Lasting 24 Hr Hydration ,for Combination Skin, No Added Fragrance ,Non-Comedogenic ,Doctor Recommended Sensitive Skincare Brand
  • CETAPHIL DAILY HYDRATING LOTION FOR COMBINATION SKIN: Instantly hydrates and locks in moisture for 24 hours to protect skin from dryness
  • IMMEDIATE AND INTENSE HYDRATION: Hyaluronic acid and powerful moisturizing agents provide long lasting hydration
  • FAST ABSORBING, LIGHTWEIGHT FORMULA: Non-greasy moisturizer won't clog pores
  • NO ADDED FRAGRANCE AND HYPOALLERGENIC: Clinically tested to be gentle on combination, sensitive skin
  • DESIGNED FOR SENSITIVE SKIN: All CETAPHIL products are effective yet non-irritating
  • FROM THE #1 DOCTOR RECOMMENDED SENSITIVE SKINCARE BRAND
SaleBestseller No. 3
La Roche-Posay Toleriane Double Repair Face Moisturizer, Daily Moisturizer Face Cream with Ceramide and Niacinamide for All Skin Types, Oil Free, Fragrance Free
  • Toleriane Double Repair Face Moisturizer is formulated with dermatologist-recommended ingredients including ceramide-3, niacinamide, glycerin and La Roche-Posay Prebiotic Thermal Water
  • Double action helps repair skin’s natural protective barrier after 1-hour and provide up to 48-hour hydration. Produces a unique prebiotic action on the skin microbiome and restores healthy-looking skin
  • Its lightweight cream texture easily absorbs into the skin to provide immediate comfort
  • Suitable for all skin types, including sensitive. Fragrance free, paraben free, oil free, alcohol free, non comedogenic
  • Formulated with Ceramide-3: to help retain moisture and maintain a healthy skin barrier. Niacinamide: helps restore skin's moisture barrier, and visibly fading skin discolorations. Glycerin: hydrates skin
Bestseller No. 4
Paulas Choice--SKIN PERFECTING 2% BHA Liquid Salicylic Acid Exfoliant--Facial Exfoliant for Blackheads, Enlarged Pores, Wrinkles & Fine Lines, 4 oz Bottle
  • GENTLE NON-ABRASIVE LEAVE-ON EXFOLIATOR: with 2% BHA (Beta hydroxy acid) to unclog & diminish enlarged pores, exfoliate dead skin cells, smooth wrinkles & brighten & even out skin tone. Combats redness, wrinkles, aging, enlarged pores, & blackheads. PACKAGING MAY VARY.
  • Dramatically improves skin's texture for radiant youthful even-toned skin. Beta hydroxy acid (BHA also known as salicylic acid) mimics the natural exfoliation process of younger skin by helping it shed extra layers while unclogging and clearing pores.
  • HYDRATE, BRIGHTEN & SMOOTH FINE LINES: Our unique, non-abrasive, leave-on exfoliant is gentle enough for daily use on all skin types. Exfoliates dead skin cells while clearing pores for a more even tone, plus it visibly reduces fine lines & wrinkles.
  • Paula's Choice facial exfoliants are gentler on delicate skin of the face & neck than an abrasive face scrub, which can cause micro-tears. A BHA leave-on exfoliator delivers hydration & can exfoliate directly inside the pore & improve how the pore works.
  • Paula's Choice Skincare makes products that work. No fragrance, no parabens, no fluff. Just effective, science-backed formulas that target any concern from wrinkles to breakouts.
SaleBestseller No. 5
TruSkin Vitamin C Serum for Face, Anti Aging Serum with Hyaluronic Acid, Vitamin E, Organic Aloe Vera and Jojoba Oil, Hydrating & Brightening Serum for Dark Spots, Fine Lines and Wrinkles, 1 fl oz
  • ANTI AGING FACE SERUM - Vitamin C blends with Botanical Hyaluronic Acid, Vitamin E, Witch Hazel, and Jojoba Oil in an anti aging, skin brightening formula designed to improve wrinkles and dark spots
  • OUR CUSTOMERS KNOW BEST - Don't just take our word for it, see thousands of reviews from real Amazon customers rave about brighter, fresher looking skin
  • PLANT-BASED FORMULATION - No added synthetic colors, fragrances, parabens, phthalates, sulfates, PEGs, or GMOs. Our active botanicals combine in a silky smooth anti-aging serum that can be used day or night.
  • CERTIFIED CRUELTY FREE by Leaping Bunny, our Vitamin C facial serum is also formulated, manufactured and bottled in the USA for guaranteed freshness
  • EXTENDED MANUFACTURER GUARANTEE - Love it or your money back! If for any reason you decide this product isn't a good fit for your skin, we offer a 90-day money-back refund. The expiration date is printed on the barcode sticker attached to the packaging.
SaleBestseller No. 6
NYX PROFESSIONAL MAKEUP Makeup Setting Spray - Matte Finish, Long-Lasting Vegan Formula (Packaging May Vary)
  • Matte Setting Spray: For a matte makeup look that stays put, use our lightweight setting spray to reduce shine and leave a fresh, just applied look all day; Works with all makeup including foundation, eyeshadow, and powder
  • Lock In Your Look: Get a smooth, long lasting finish for your makeup with this lightweight setting spray that helps extend makeup wear up to 16 hours, until it's time to party
  • Face From Foundation To Finish: Complete your makeup look with our full line of face products to aid in color correction and coverage from concealer, blush, bronzer, foundations and contouring to palettes and powders
  • Cruelty Free Cosmetics: We believe animals belong in our arms, not in a lab; All of our makeup is certified and acknowledged by PETA as a cruelty free brand; We don't test any of our products on animals
  • Discover NYX Professional Makeup: Try all of our professional makeup products today from eyeshadow, eyeliner, and false lashes to liquid lipstick, lip gloss, primer, concealer, setting sprays and eyebrow makeup
SaleBestseller No. 7
Sheet mask by Glam Up Facial Sheet Mask 12 Combo (Pack of 12) - Face Masks Skincare, Hydrating Face Masks, Moisturizing, Brightening and Soothing, Beauty Mask For All Skin Type
  • ACTIVE INGREDIENTS - Face Masks Skincare with the most natural ingredients like Shea Butter, Aloe, Tea Tree, Peppermint, Green Tea, Lemon and many more beneficial ingredients. From acne to dryness, this combo is perfect for every skin concern.
  • SKINCARE ESSENTIALS - Brightening, Hydrating, Calming and Moisturizing facial sheet masks. An assortment of treatments curated to enhance the natural glow of all skin types.
  • NOT TESTED ON ANIMALS - Bye, cruelly tested on animals! Leaping Bunny certified, theses sheet masks are Cruelty Free.
  • REASONABLE PRICE - Enjoy12 high quality skin beneficial results with the most affordable price in the market.
  • BEAUTY GIFT SKINCARE SET - This multi-collection of Korean sheet mask recipes is the perfect gift choice to please all skin types and concerns. Be sure to add this to the gift idea list for women, men, teens, girls, boys, or holidays
Bestseller No. 8
Rael Miracle Clear Barrier Cream - Daily Moisturizer with Succinic Acid, Vitamin B, for Oily Skin, Paraben-Free, Vegan (1.8 oz)
  • FOR ACNE-PRONE SKIN - Specially formulated for oily skin, acne, large or clogged pores
  • POWERED BY NATURE - Infused with Succinic Acid, strengthening Minerice Enzyme Complex, and moisturizing Vitamin B5 Panthenol
  • PROTECTIVE - Supports your skin's barrier health and cares for future breakouts
  • LIGHTWEIGHT - Provides long-lasting moisturization without leaving skin feeling greasy
  • POWERFULLY GENTLE - Free of parabens, phthalates, sulfates, silicones, and artificial fragrance. Non-irritating, non-drying and safe for daily use for all skin types
SaleBestseller No. 9
Cetaphil Face Moisturizer, Gentle Clear Mattifying Acne Moisturizer With 0.5% Salicylic Acid, Hydrates and Treats Sensitive Acne Prone Skin, Skin Care for Sensitive Skin, 3oz
  • HYDRATES & CLEARS BREAKOUTS: Shine-free hydration with .5% Salicylic Acid clears and prevents breakouts while improving tone and texture in sensitive skin
  • BOTANICAL & PREBIOTIC COMPLEX SOOTHES ACNE REDNESS: Formulated with botanicals and prebiotic complex to help nourish skin and soothe acne redness
  • DEFENDS AGAINST FIVE SIGNS OF SKIN SENSITIVITY: Defends against five signs of skin sensitivity including a weakened skin barrier, irritation, roughness, tightness, and dryness
  • DERMATOLOGIST RECOMMENDED for Sensitive Skin
  • DEFENDS AGAINST 5 SIGNS OF SKIN SENSITIVITY: Dryness, irritation, roughness, tightness and a weakened skin barrier
Bestseller No. 10
Vichy Mineral 89 Hyaluronic Acid Face Serum, Facial Gel Moisturizer and Pure Hyaluronic Acid Moisturizing and Hydrating Serum for Sensitive Skin and Dry Skin
  • Our best-selling hyaluronic acid serum is formulated with Pure Hyaluronic Acid and 15 Mineral-Rich Vichy Volcanic Water to strengthen & repair your skin barrier
  • This daily hydrating and plumping booster has been clinically tested by 175 dermatologists on 1600 women worldwide
  • Safe and effective for all skin types, in a minimalist, fragrance free formula with only 11 ingredients. Alcohol free. Silicone Free
  • Lightweight, fast-absorbing translucent booster
  • Accepted by the National Eczema Association

Things to Consider When Buying the Best Drugstore Night Creams for Acne Prone Skin

Ingredients

When it comes to choosing the best drugstore night cream for acne prone skin, the most important thing to consider is the ingredients. If you’re particularly allergic to a specific ingredient, make sure to only choose products that don’t contain it. This way, you won’t experience allergies or irritation when using a drugstore night cream.

Price

Another important thing to consider is the price. You shouldn’t always chase the cheapest product on the market as it can cause problems in the long run. Similarly, just because a product is expensive doesn’t mean that it’s the right product for you. Make sure to do your due diligence when shopping for the best drugstore night cream for acne prone skin.

Avoid Harsh Chemicals

When looking for the best drugstore night cream for acne prone skin, it’s better to avoid harsh chemicals. Generally, it’s better to look for a product that doesn’t contain synthetic fragrances, parabens, sulfates, phthalates, etc. Even the reputable products can sometimes contain these chemicals, it’s important to look at the formula. Too much of these chemicals can be bad for you.

Star Rating

If a product is well-received on Amazon, chances are it’s usually pretty good. These reviews are generally a testament to the efficacy of a product. When shopping for the best drugstore night cream for acne prone skin, you should usually go with product with the star rating of 3. 5 or more. The higher the better!

Read Customer Reviews

Reading customer reviews can also be helpful when purchasing the best drugstore night cream for acne prone skin. It’s possible that someone else who has the same needs as you has already tried and reviewed the product. Reading their review will give you an idea on whether or not the drugstore night cream you’re looking to buy is worth your time and money.

Brand Name

Finally, when it comes to beauty, skincare, or hair care products, it’s usually better to stick with reputable products. There are so many products available on the market, but the brands which have stood the test of time are the ones that you should generally go for. At the same time, don’t be afraid of experimenting with new products.

Patch Test

No matter which drugstore night cream you’re considering, it’s important to do a patch test first (even if a product is well-received). Everyone is different and so are their needs. So, always be sure to do a patch test when you try out a new product.

Conclusion

It can be challenging to find the best drugstore night cream for acne prone skin. However, we’ve done all the heavy-lifting for you. We hope this article helped you find the best drugstore night cream for your needs.

Which one of these drugstore night creams are you going to try? Let us know in the comments below. If you have any questions, ask away.

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