10 Best Creams for Acne in 2022

With so many options, finding the best cream for acne can be overwhelming. There are so many things to consider such as ingredients, formula, brand name, price, and so much more. Needless to say, this can be pretty time-consuming.

To save you the hassle, we researched hundreds of products and sifted through thousands of customer reviews. Then we checked the ingredients, formula, efficacy, and price. Based on this, we bring you the best cream for acne. Let’s have a look.

Top 10 Best Creams for Acne

Bestseller No. 1
Neutrogena Rapid Clear Stubborn Acne Spot Treatment Gel with Maximum Strength 10% Benzoyl Peroxide Acne Treatment Medication, Pimple Cream for Acne Prone Skin Care, 1 oz
  • 1-ounce tube of Neutrogena Rapid Clear Stubborn Acne Spot Treatment Gel with maximum-strength 10% benzoyl peroxide acne medication to help fight acne and prevent future breakouts for clearer looking skin
  • This effective acne-fighting spot gel is clinically proven to rapidly reduce the size and redness of stubborn acne in just 2 hours and actively fights breakouts, for continuous improvement in skin's appearance throughout the day
  • Its maximum strength formula contains 10% benzoyl peroxide, the acne medication dermatologists recommend most for clearer skin without a prescription
  • From a dermatologist recommended brand, this maximum-strength daily stubborn acne treatment is specially formulated for acne-prone skin to help manage acne and clear breakouts
  • Cleanse skin thoroughly before applying acne pimple spot treatment gel then proceed to cover affected area with a thin layer of acne gel 1 to 3 times daily
SaleBestseller No. 3
CeraVe Acne Foaming Cream Cleanser | Acne Treatment Face Wash with 4% Benzoyl Peroxide, Hyaluronic Acid, and Niacinamide | Cream to Foam Formula | Fragrance Free & Non Comedogenic | 5 Oz
  • This product is non-sealed
  • [ ACNE FACE WASH WITH BENZOYL PEROXIDE ] This benzoyl peroxide face wash helps clear acne, pimples, whiteheads, and blackheads from skin's surface and helps prevent new acne from forming & allows skin to heal
  • [ CREAM CLEANSER TO FOAMING CLEANSER ] This CeraVe face wash dispenses and applies as a soothing & creamy texture and transforms into a  foam as you lather into skin. Gently remove dirt and excess oil without leaving skin feeling stripped of moisture
  • [ HYDRATING ACNE WASH ] Formulated with hyaluronic Acid to help retain skin's natural moisture and niacinamide to help calm skin. Fragrance free and non-comedogenic
  • [ 3 ESSENTIAL CERAMIDES ] Ceramides are found naturally in the skin and make up 50% of the lipids in the skin barrier. All CeraVe products, formulated with three essential ceramides (1, 3, 6-II)to help maintain the skin’s natural barrier.
  • [ DEVELOPED WITH DERMATOLOGISTS ] CeraVe Skincare is developed with dermatologists and has products suitable for dry skin, sensitive skin, oily skin, acne-prone, and more.
Bestseller No. 5
Acne Treatment for Face, Salicylic Acid Acne Cream Back Acne Treatment Cream for Teens & Adults Anti-acne Moisturizer Pimple Cream Butt Acne Clearing Cream, Acne Spot Treatment for Breakouts Blemish
  • ADVANCED CYSTIC ACNE TREATMENT: Our cystic acne treatment cream reduces cystic acne pimples, whiteheads, and blackheads. specially developed for all types of acne-prone skin, gentle, moisturizing, and repairing by reducing oil production, which helps to prevent scarring and future breakouts.
  • ACNE CLEARING TREATMENT WITH NATURE INGREDIENTS & GENTLE: Repair Acne Treatment is made of all-natural ingredients, the main active ingredient: 3% AHA, 1.5%BHA, 0.1% ZINC PAC, 4% Latic Acid, and 0.2% VITAMIN B6, which has the function of softening the acne skin, improve skin smoothness and gently exfoliating the acne area.
  • DIRECTIONS FOR USE THE ACNE DOTS TREATMENT: Take an appropriate amount of this Cystic Acne Treatment Cream and apply it evenly on the acne-producing area of ​​the face and body like the Back, Hip, Chest, Neck, Shoulders, and upper arms. Apply it 2 times a day, or apply it 2-3 times if it is a serious condition for 4 weeks at least.
  • FAST RESULTS USING THE ACNE SCAR REMOVAL CREAM - Immediate results within days. Specially formulated to moisturize your skin while gently healing butt acne and eliminating dark spots. Clears up any current acne while prepping your skin for an acne-free complexion.
  • BUY WITH CONFIDENCE: The spot acne treatment was made with a muti kind of acid, please use a small patch on your neck or after the ear for 10 minutes. Any problem please free to contact us. We'll immediately make everything right for you within 24 hours! 100% Satisfaction Warranty.
SaleBestseller No. 6
Acne Medication Face Cream - Made in USA Fast Acting Drug AcneTreatment For Stubborn Pimple Blackhead Whitehead Blemish - Soothing Acne Moisturizer for Inflammation Relief & Acne Scar Prevention 2oz
  • Works Fast - Simply Vital Acne Face Cream is a unique acne therapy formula. It combines the clinically proven power of 2% salicylic acid with gentle skincare that is suitable for many skin types. It's ideal for treating and reducing white- and blackheads, as well as keeping your face clear by preventing future breakouts. Achieve perfectly clear skin with Simply Vital!
  • Made with Naturals - Besides salicylic acid, your formula is enhanced with soothing natural ingredients like green tea, tea tree oil, and apple cider vinegar. They help to soothe the breakouts and irritation, clear the pores and fade acne scars. The aloe vera extract helps to hydrate the skin and protect it from possible drying. You can treat acne and care for your skin with one product!
  • Cure, Prevent & Protect - Enjoy clear your clear and power up your confidence with Simply Vital acne cream! Our professional formula will relieve existing inflammation, remove acne and blackheads as well as prevent future breakouts by dissolving dead skin cells and oil that can clog up your pores. Our cream will also care for your complexion and fade out all the imperfections.
  • Safe & Effective OTC Cream - Simply Vital Acne Face Cream is a doctor-recommended and approved OTC treatment with clinically proven strength and gentle supportive formula. Our face cream has been tested for safety and effectiveness and can boast OTC power with premium comfort and convenience. We use only premium quality ingredients and our production meets the highest standards of quality control.
  • Premium Customer Support - Your health and confidence are the main priorities for Simply Vital. We follow strict compliance guidelines - the product is made in the United States, is cruelty-free, and was not tested on animals. We are always happy to hear your questions and suggestions. If you are somewhat unsatisfied with your purchase, please contact us, and we'll make things right for you!
SaleBestseller No. 7
Lion PAIR Acne Cream W Reduces Itching Blemishes Rashes Redness 2x24 g
  • Type : Cream
  • Scent : Lavender Flower Extract
  • Size : 24 g
  • Quantity : 2 Tube
Bestseller No. 8
Proactiv 3 Step Acne Treatment - Benzoyl Peroxide Face Wash, Repairing Acne Spot Treatment for Face and Body, Exfoliating Toner - 30 Day Complete Acne Skin Care Kit
  • THE ORIGINAL ACNE KIT THAT STARTED A SKINCARE REVOLUTION - Designed specifically for acne-prone skin, Proactiv Solution delivers finely-milled benzoyl peroxide deep into your pores to help stop acne-causing bacteria in its tracks and prevent breakouts.
  • YOU NEED MORE THAN A PIMPLE CREAM - Proactiv Solution is a powerful, comprehensive acne treatment system that goes deep into your pores, removes impurities and helps prevent future flare ups.
  • YOUR SKIN ROUTINE, MADE EASY - Just 3 steps a day gets you on your way to clear, radiant skin.
  • SAFE FOR DIFFERENT AGES AND SKIN TYPES - Proactiv's 3-Step Kit provides the same powerful skin care for teens and adults, and is great for sensitive skin.
  • A WIN FOR YOUR SKIN - Our complete treatment system can clear existing acne blemishes and prevent new breakouts from occurring. What's not to love.
  • This kit includes: Proactiv Solution Renewing Cleanser, 2 FL. OZ. ; Proactiv Solution Revitalizing Toner, 2 FL. OZ. ; Proactiv Solution Repairing Treatment, 1 FL. OZ.
SaleBestseller No. 9
Clearasil Stubborn Acne Control 5 in 1 Spot Treatment Cream, 1 oz (Pack of 6)
  • 24 Hour Control. Maximum Strength
  • Helps to clear existing pimples
  • Helps prevent new pimples from forming
  • Penetrates pores to treat pimples
  • Dermatologist tested
SaleBestseller No. 10
Neutrogena On-The-Spot Acne Spot Treatment with 2.5% Benzoyl Peroxide Acne Treatment Medication to Treat Face Acne, Gentle Benzoyl Peroxide Pimple Cream for Acne Prone Skin Care.75 oz
  • 75-ounce tube of Neutrogena On-The-Spot Acne Spot Treatment cream with benzoyl peroxide to fight acne while gentle on skin
  • Vanishing cream formula of this acne spot treatment is lightweight, absorbs quickly and works invisibly hour after hour to give long-lasting acne treatment
  • On-The-Spot treatment is clinically proven to be so effective that skin starts getting clearer on day 1 to without over-drying, stinging or burning skin
  • This gentle daily acne blemish treatment can be used up to three times a day. It's formulated with 2.5% benzoyl peroxide acne medicine, to help treat and prevent acne
  • The acne-fighting formula goes deep down into pores to kill acne bacteria that causes pimples and helps stop new ones from forming

Things to Consider When Buying the Best Creams for Acne

Ingredients

When it comes to choosing the best cream for acne, the most important thing to consider is the ingredients. If you’re particularly allergic to a specific ingredient, make sure to only choose products that don’t contain it. This way, you won’t experience allergies or irritation when using a cream.

Price

Another important thing to consider is the price. You shouldn’t always chase the cheapest product on the market as it can cause problems in the long run. Similarly, just because a product is expensive doesn’t mean that it’s the right product for you. Make sure to do your due diligence when shopping for the best cream for acne.

Avoid Harsh Chemicals

When looking for the best cream for acne, it’s better to avoid harsh chemicals. Generally, it’s better to look for a product that doesn’t contain synthetic fragrances, parabens, sulfates, phthalates, etc. Even the reputable products can sometimes contain these chemicals, it’s important to look at the formula. Too much of these chemicals can be bad for you.

Star Rating

If a product is well-received on Amazon, chances are it’s usually pretty good. These reviews are generally a testament to the efficacy of a product. When shopping for the best cream for acne, you should usually go with product with the star rating of 3. 5 or more. The higher the better!

Read Customer Reviews

Reading customer reviews can also be helpful when purchasing the best cream for acne. It’s possible that someone else who has the same needs as you has already tried and reviewed the product. Reading their review will give you an idea on whether or not the cream you’re looking to buy is worth your time and money.

Brand Name

Finally, when it comes to beauty, skincare, or hair care products, it’s usually better to stick with reputable products. There are so many products available on the market, but the brands which have stood the test of time are the ones that you should generally go for. At the same time, don’t be afraid of experimenting with new products.

Patch Test

No matter which cream you’re considering, it’s important to do a patch test first (even if a product is well-received). Everyone is different and so are their needs. So, always be sure to do a patch test when you try out a new product.

Conclusion

It can be challenging to find the best cream for acne. However, we’ve done all the heavy-lifting for you. We hope this article helped you find the best cream for your needs.

Which one of these creams are you going to try? Let us know in the comments below. If you have any questions, ask away.

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